English

業績

2024年度

原著論文

  1. Hamano S, Noguchi T, Asai Y, Ito R, Komatsu R, Sato T, Inoue A, Maruyama T, Kudo TA, Hirata Y, Shindo S, Uchida Y, Hwang GW, Matsuzawa A. Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos. Cell Death Discov. 2024 Feb 12;10(1):74. doi: 10.1038/s41420-024-01838-2. PMID: 38346947; PMCID: PMC10861449.
  2. Arime Y, Saitoh Y, Ishikawa M, Kamiyoshihara C, Uchida Y, Fujii K, Takao K, Akiyama K, Ohkawa N. Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia. Neuropsychopharmacology. 2024 Mar;49(4):720-730. doi: 10.1038/s41386-023-01769-z. Epub 2023 Dec 4. PMID: 38049583; PMCID: PMC10876596.
  3. Kataoka H, Akiyoshi T, Uchida Y, Imaoka A, Terasaki T, Ohtani H. The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B1. J Pharm Sci. 2024 May;113(5):1376-1384. doi: 10.1016/j.xphs.2024.02.012. Epub 2024 Mar 1. PMID: 38432624.
  4. Yuasa H, Morino N, Wagatsuma T, Munekane M, Ueda S, Matsunaga M, Uchida Y, Katayama T, Katoh T, Kambe T. ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn2+ to Golgi α-mannosidase II. J Biol Chem. 2024 Jun;300(6):107378. doi: 10.1016/j.jbc.2024.107378. Epub 2024 May 16. PMID: 38762179; PMCID: PMC11209640.
  5. Ramsay E, Montaser AB, Niitsu K, Urtti A, Auriola S, Huttunen KM, Uchida Y, Kidron H, Terasaki T. Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study. Mol Pharm. 2024 Jul 1;21(7):3204-3217. doi: 10.1021/acs.molpharmaceut.3c01210. Epub 2024 May 29. PMID: 38809137.
  6. Yoshimori T, Kawami M, Kumagai Y, Futatsugi S, Yumoto R, Uchida Y, Takano M. Abemaciclib-induced epithelial-mesenchymal transition mediated by cyclin-dependent kinase 4/6 independent of cell cycle arrest pathway. Int J Biochem Cell Biol. 2024 Jul;172:106601. doi: 10.1016/j.biocel.2024.106601. Epub 2024 May 29. PMID: 38821314.
  7. Hashimoto Y, Besmond C, Boddaert N, Munnich A, Campbell M. A loss of function mutation in CLDN25 causing Pelizaeus-Merzbacher-like leukodystrophy. Hum Mol Genet. 2024 Jun 5;33(12):1055-1063. doi: 10.1093/hmg/ddae038. PMID: 38493358; PMCID: PMC11153337.
  8. Hashimoto Y, Greene C, Hanley N, Hudson N, Henshall D, Sweeney KJ, O’Brien DF, Campbell M. Pumilio-1 mediated translational control of claudin-5 at the blood-brain barrier. Fluids Barriers CNS. 2024 Jun 19;21(1):52. doi: 10.1186/s12987-024-00553-5. PMID: 38898501; PMCID: PMC11188261.

総説

  1. 前田祐希、川見昌史、内田康雄、血液クモ膜関門：血液脳関門とは異なる輸送分子機構をもつ新たな中枢関門、膜、49巻2号、p99-106、2024年
  2. 赤井美月、川見昌史、内田康雄、SWATH-MS法を利用した金属輸送体の機能解析、生体の科学、75巻2号、p116-121、2024年
  3. <Preview> Hashimoto Y, Campbell M. Eyes on glutamate in angiogenesis and barrier formation. Neuron. 2024 Jun 19;112(12):1895-1897. doi: 10.1016/j.neuron.2024.05.020. PMID: 38901398.

2023年度

原著論文

  1. Iio K, Hashimoto K, Nagumo Y, Amezawa M, Hasegawa T, Yamamoto N, Kutsumura N, Takeuchi K, Ishikawa Y, Yamamoto H, Tokuda A, Sato T, Uchida Y, Inoue A, Tanimura R, Yanagisawa M, Nagase H, Saitoh T. Design and Synthesis of Orexin 1 Receptor-Selective Agonists. J Med Chem. 2023 Apr 27;66(8):5453-5464. doi: 10.1021/acs.jmedchem.2c01773. Epub 2023 Apr 12. PMID: 37043436.
  2. Ishiguro H, Mizuno T, Uchida Y, Sato R, Sasaki H, Nemoto S, Terasaki T, Kusuhara H. Characterization of proteome profile data of chemicals based on data-independent acquisition MS with SWATH method. NAR Genom Bioinform. 2023 Mar 11;5(1):lqad022. doi: 10.1093/nargab/lqad022. PMID: 36915410; PMCID: PMC10006730.
  3. Wang Y, Sakaguchi M, Sabit H, Tamai S, Ichinose T, Tanaka S, Kinoshita M, Uchida Y, Ohtsuki S, Nakada M. COL1A2 inhibition suppresses glioblastoma cell proliferation and invasion. J Neurosurg. 2022 Aug 5;138(3):639-648. doi: 10.3171/2022.6.JNS22319. PMID: 35932265.

総説

  1. 内田康雄、次世代型定量プロテオミクスによる中枢関門トランスポーター研究、薬剤学、83巻2号、p72-77、2023年